Jane Austen wrote or polished all six of her novels in Chawton, a cottage on her brother's property. She lived in this house from her thirties until her family sent her to Winchester (I believe) to get specialized treatment for a debilitating illness. She had Addison's disease, in case you didn't know-- I didn't. In laymen's terms, that means her liver shut down. She was poisoned to death by slowly accumulating toxins.
Addison's was not understood/ discovered in the early nineteenth century, so whatever treatment that doctor in Winchester thought he was prescribing, it certainly wasn't going to do any good.